Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Kit  KIT proto-oncogene receptor tyrosine kinase   (Synonyms: belly-spot, CD117, c-KIT, Dominant white spotting, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Steel Factor Receptor, Tr-kit)
Results	Reference
1	J:36230 Bernex F, De Sepulveda P, Kress C, Elbaz C, Delouis C, Panthier JJ, Spatial and temporal patterns of c-kit-expressing cells in WlacZ/+ and WlacZ/WlacZ mouse embryos. Development. 1996 Oct;122(10):3023-33
1	J:198502 Clarke RL, Yzaguirre AD, Yashiro-Ohtani Y, Bondue A, Blanpain C, Pear WS, Speck NA, Keller G, The expression of Sox17 identifies and regulates haemogenic endothelium. Nat Cell Biol. 2013 May;15(5):502-10
1	J:213676 Dartsch N, Schulte D, Hagerling R, Kiefer F, Vestweber D, Fusing VE-cadherin to alpha-catenin impairs fetal liver hematopoiesis and lymph but not blood vessel formation. Mol Cell Biol. 2014 May;34(9):1634-48
1	J:257598 Eich C, Arlt J, Vink CS, Solaimani Kartalaei P, Kaimakis P, Mariani SA, van der Linden R, van Cappellen WA, Dzierzak E, In vivo single cell analysis reveals Gata2 dynamics in cells transitioning to hematopoietic fate. J Exp Med. 2018 Jan 2;215(1):233-248
1*	J:233088 Frame JM, Fegan KH, Conway SJ, McGrath KE, Palis J, Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity. Stem Cells. 2016 Feb;34(2):431-44
1	J:227634 Gama-Norton L, Ferrando E, Ruiz-Herguido C, Liu Z, Guiu J, Islam AB, Lee SU, Yan M, Guidos CJ, Lopez-Bigas N, Maeda T, Espinosa L, Kopan R, Bigas A, Notch signal strength controls cell fate in the haemogenic endothelium. Nat Commun. 2015;6:8510
1	J:345606 Gonzalez Galofre ZN, Kilpatrick AM, Marques M, Sa da Bandeira D, Ventura T, Gomez Salazar M, Bouilleau L, Marc Y, Barbosa AB, Rossi F, Beltran M, van de Werken HJG, van IJcken WFJ, Henderson NC, Forbes SJ, Crisan M, Runx1+ vascular smooth muscle cells are essential for hematopoietic stem and progenitor cell development in vivo. Nat Commun. 2024 Feb 23;15(1):1653
1	J:253071 Iizuka K, Yokomizo T, Watanabe N, Tanaka Y, Osato M, Takaku T, Komatsu N, Lack of Phenotypical and Morphological Evidences of Endothelial to Hematopoietic Transition in the Murine Embryonic Head during Hematopoietic Stem Cell Emergence. PLoS One. 2016;11(5):e0156427
1	J:259078 Johnson KD, Kong G, Gao X, Chang YI, Hewitt KJ, Sanalkumar R, Prathibha R, Ranheim EA, Dewey CN, Zhang J, Bresnick EH, Cis-regulatory mechanisms governing stem and progenitor cell transitions. Sci Adv. 2015 Sep;1(8):e1500503
1	J:214903 Kataoka H, Hayashi M, Kobayashi K, Ding G, Tanaka Y, Nishikawa S, Region-specific Etv2 ablation revealed the critical origin of hemogenic capacity from Hox6-positive caudal-lateral primitive mesoderm. Exp Hematol. 2013 Jun;41(6):567-581.e9
1	J:325982 Klaus A, Clapes T, Yvernogeau L, Basu S, Weijts B, Maas J, Smal I, Galjart N, Robin C, CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development. Cell Rep. 2022 Jun 14;39(11):110957
1	J:210754 Lan Y, He W, Li Z, Wang Y, Wang J, Gao J, Wang W, Cheng T, Liu B, Yang X, Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation. Blood. 2014 Apr 3;123(14):2161-71
1	J:254246 Mehta C, Johnson KD, Gao X, Ong IM, Katsumura KR, McIver SC, Ranheim EA, Bresnick EH, Integrating Enhancer Mechanisms to Establish a Hierarchical Blood Development Program. Cell Rep. 2017 Sep 19;20(12):2966-2979
1	J:85840 Nadin BM, Goodell MA, Hirschi KK, Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood. 2003 Oct 1;102(7):2436-43
1	J:264757 Neo WH, Booth CAG, Azzoni E, Chi L, Delgado-Olguin P, de Bruijn MFTR, Jacobsen SEW, Mead AJ, Cell-extrinsic hematopoietic impact of Ezh2 inactivation in fetal liver endothelial cells. Blood. 2018 May 17;131(20):2223-2234
1	J:316414 Neo WH, Meng Y, Rodriguez-Meira A, Fadlullah MZH, Booth CAG, Azzoni E, Thongjuea S, de Bruijn MFTR, Jacobsen SEW, Mead AJ, Lacaud G, Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors. Nat Commun. 2021 Dec 2;12(1):7019
1	J:264119 Pichol-Thievend C, Betterman KL, Liu X, Ma W, Skoczylas R, Lesieur E, Bos FL, Schulte D, Schulte-Merker S, Hogan BM, Oliver G, Harvey NL, Francois M, A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development. Development. 2018 May 17;145(10):dev160184
1	J:345408 Pv A, Mehatre SH, Verfaillie CM, Alam MT, Khurana S, Glycolytic state of aortic endothelium favors hematopoietic transition during the emergence of definitive hematopoiesis. Sci Adv. 2024 Feb 16;10(7):eadh8478
1	J:239420 Rantakari P, Jappinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M, Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016 Oct 20;538(7625):392-396
1	J:327069 Sa da Bandeira D, Kilpatrick AM, Marques M, Gomez-Salazar M, Ventura T, Gonzalez ZN, Stefancova D, Rossi F, Vermeren M, Vink CS, Beltran M, Henderson NC, Jung B, van der Linden R, van de Werken HJG, van Ijcken WFJ, Betsholtz C, Forbes SJ, Cuervo H, Crisan M, PDGFRbeta(+) cells play a dual role as hematopoietic precursors and niche cells during mouse ontogeny. Cell Rep. 2022 Jul 19;40(3):111114
1	J:260880 Saito K, Nobuhisa I, Harada K, Takahashi S, Anani M, Lickert H, Kanai-Azuma M, Kanai Y, Taga T, Maintenance of hematopoietic stem and progenitor cells in fetal intra-aortic hematopoietic clusters by the Sox17-Notch1-Hes1 axis. Exp Cell Res. 2018 Apr 1;365(1):145-155
1	J:207377 Sanalkumar R, Johnson KD, Gao X, Boyer ME, Chang YI, Hewitt KJ, Zhang J, Bresnick EH, Mechanism governing a stem cell-generating cis-regulatory element. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):E1091-100
1*	J:316415 Soukup AA, Matson DR, Liu P, Johnson KD, Bresnick EH, Conditionally pathogenic genetic variants of a hematopoietic disease-suppressing enhancer. Sci Adv. 2021 Dec 10;7(50):eabk3521
1	J:295045 Soukup AA, Zheng Y, Mehta C, Wu J, Liu P, Cao M, Hofmann I, Zhou Y, Zhang J, Johnson KD, Choi K, Keles S, Bresnick EH, Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer. J Clin Invest. 2019 Mar 1;129(3):1180-1192
1	J:165571 Yokomizo T, Dzierzak E, Three-dimensional cartography of hematopoietic clusters in the vasculature of whole mouse embryos. Development. 2010 Nov;137(21):3651-61
1	J:174699 Yokomizo T, Ng CE, Osato M, Dzierzak E, Three-dimensional imaging of whole midgestation murine embryos shows an intravascular localization for all hematopoietic clusters. Blood. 2011 Jun 9;117(23):6132-4
1	J:117242 Yokomizo T, Takahashi S, Mochizuki N, Kuroha T, Ema M, Wakamatsu A, Shimizu R, Ohneda O, Osato M, Okada H, Komori T, Ogawa M, Nishikawa S, Ito Y, Yamamoto M, Characterization of GATA-1(+) hemangioblastic cells in the mouse embryo. EMBO J. 2007 Jan 10;26(1):184-96
1*	J:235365 Yzaguirre AD, Speck NA, Insights into blood cell formation from hemogenic endothelium in lesser-known anatomic sites. Dev Dyn. 2016 Oct;245(10):1011-28